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This clinical observation has been attributed to less-well-developed compensatory mechanisms (eg, vasoconstriction, tachycardia) and greater sensitivity of the immature myocardium to myocardial depressants.The cardiac and respiratory effects of the drugs and technique chosen should avoid distortion of hemodynamic measurements.The PK profile for midazolam and 1 hydroxy midazolam was determined by mathematical modelling of the concentrations measured in blood samples drawn from a venous cannula.
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Anaesthesia UK : Paediatric anaesthesia

Pediatric Anesthesia: List of Issues - Wiley Online Library

A total of 263 venous blood samples were analysed. The Force Data extracted included demographic information, case information, written comments, and the use of medications common in the treatment of laryngospasm and bronchospasm.Address the queries and fears of the child as well as those of the parent. Anne Frank The newborn is at a greater risk of cooling when exposed to a cold environment because the ratio of body surface area to body weight is double that of older patients.